Maak daarom direct een free of charge account aan. Daarmee heb je ook toegang tot onze webinars. Registreren duurt minder dan een minuut en is helemaal gratis.
1996, very first mesoscopic demand density waves devices; and very first electrical measurements on only one metal nanocluster among nanoelectrodes
[Laughs] ‘It was certainly an excellent danger! At the time, I had been very well informed that it could go Mistaken and that I could turn out to be much less thriving, but I just disregarded that. Curiosity has normally been my strongest driving pressure. And fortuitously it all labored out.’
2007, initial true-time detection of strand Trade in homologous recombination by RecA; discovery of a minimal persistence duration of finishes of microtubules; and settled the system of biosensing with carbon nanotubes
2015, discovery that condensin is actually a really flexible protein construction; and to start with detection of DNA knots utilizing nanopores
Illustration (3) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in grey, the rim of the pore is highlighted in purple, as well as a 3D rendering of the movement from the DNA rod is exhibited.
Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with study from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his study has centered on finding out cell division with microbes on chip, when his final curiosity is in the course of acknowledging synthetic cells.
Atomic pressure microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA in a cooperative trend
This "Cited by" depend features citations to the following posts in Scholar. The ones marked * could possibly be unique within the post inside the profile.
Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-making course of action
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
‘That concerns the synthetic mobile, as Portion of the Dutch BaSyC initiative. Craig Venter seemed top rated-down in Individuals https://www.ceesdekker.net times and identified about five hundred genes which might be minimally demanded for any performing cell. We wish to glance base-up: how do we go from the several molecules to an entire Organic process?
2005, discovery from the system of DNA uncoiling by topoisomerase enzymes; discovery of long-array conformational changes in Mre11/DNA repair service complexes; and first power measurements with a DNA molecule inside a nanopore
It absolutely was a really exciting time, during which I obtained many support from Delft University of Technological innovation, where by I was a professor at time, And that i begun a number of collaborations with molecular biologists. That assisted me study a lot.’